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Ruxolitinib

CAS No.941678-49-5
Chemical Name:Ruxolitinib
Synonyms:Jakafi;Roxolitinib;Ruxolitinib;(R)-Ruxolitinib;(R)-Ruxolitinib (>90%);INCB018424 (Ruxolitinib);Ruxolitinib(INCB-018424);R-Ruxolitinib (R-INCB018424);Ruxolitinib INCB018424 Jakafi;Jakafi Ruxolitinib (INCB018424)
CBNumber:CB02499581
Molecular Formula:C17H18N6
Formula Weight:306.371
MOL File:941678-49-5.mol
Ruxolitinib Property
density : 1.40
Safety

Ruxolitinib Chemical Properties,Usage,Production

Usage
A JAK family kinase inhibitor of JAK1, JAK2 and JAK3 with IC50s of 2.7 nM, 4.5 nM and 322 nM, respectively
Usage
Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
Usage
INCB018424 is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3
Ruxolitinib Preparation Products And Raw materials
Raw materials
Preparation Products
Ruxolitinib Suppliers      Global( 81)Suppliers     
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Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979021-34692979info@tsbiochem.comCHINA 8124 58
Shanghai Witofly Chemical Co.,Ltd   sales@witofly.comCHINA 2877 52
Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
Dalian Meilun Biotech Co., Ltd. 0411-66771943；0411-667719420411-66771945sales@meilune.comCHINA 5010 58
NCE Biomedical Co.,Ltd. 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988+86-27-87599188sales@ncebiomed.comCHINA 1503 55
Taizhou Crene Biotechnology Co., Ltd. 0576-88813233 882058080576-88229589sales@taizhoukerui.comCHINA 100 57
Intelligence Pharm Science(Shanghai) Co., Ltd. 021-57898186021-37699262sales@intelligencepharm.comCHINA 450 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
PharmaBlock R&D Co. Ltd. 400 025 518886-025-86918232sales_china@pharmablock.comCHINA 5369 55
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
 
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941678-49-5 Ruxolitinib APIs (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile 1H-Pyrazole-1-propanenitrile,.beta.-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-,(.beta.R)- Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Tyrosine Kinase Inhibitors (3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile INCB018424 (Ruxolitinib) Jakafi Roxolitinib β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-(βR)-1H-pyrazole-1-propanenitrile (R)-Ruxolitinib (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazole-1-propanenitrile Ruxolitinib(INCB-018424) Ruxolitinib INCB018424 Jakafi Inhibitor Antineoplastic Jakafi Ruxolitinib (INCB018424) Anti-cancer&immunity (R)-Ruxolitinib (>90%) R-Ruxolitinib (R-INCB018424) (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile Ruxolitinib(INCB018424)
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