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C-(1H-INDOL-5-YL)-METHYLAMINE

CAS No.81881-74-5
Chemical Name:C-(1H-INDOL-5-YL)-METHYLAMINE
Synonyms:Indole-5-methanamine;INDOLE-5-METHYLAMINE;5-(aminomethyl)-indol;5-(AMINOMETHYL)INDOLE;1H-Indole-5-MethanaMine;((Indol-5-yl)Methyl)aMine;(1H-INDOL-5-YL)METHANAMINE;(1H-Indol-5-yl)methylamine;1-(1H-Indol-5-yl)MethanaMine;C-(1H-INDOL-5-YL)-METHYLAMINE
CBNumber:CB5271243
Molecular Formula:C9H10N2
Formula Weight:146.19
MOL File:81881-74-5.mol
C-(1H-INDOL-5-YL)-METHYLAMINE Property
mp : 114-118 °C
Safety
Hazard Codes : Xn
Risk Statements : 22-36/37/38
Safety Statements : 26-36
WGK Germany : 3
RTECS : NL4461500

C-(1H-INDOL-5-YL)-METHYLAMINE Chemical Properties,Usage,Production

Usage
Reactant for preparation of:• ;HIV-1 integrase inhibitors targeting the catalytic domain and its ability for interaction with LEDGF/p751• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway2• ;SCIO-469-like compounds for the inhibition of p38 MAP kinase3• ;4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles as protein kinase c theta (PKC θ) inhibitors4• ;Non-covalent thrombin inhibitors5
Usage
5-(Aminomethyl)indole is used in the synthesis of Vigabatrin (V253000) bioisosteres as inhibitors of γ-aminobutyric acid aminotransferase (GABA-AT) inhibitors.
C-(1H-INDOL-5-YL)-METHYLAMINE Preparation Products And Raw materials
Raw materials
COPPER(I) CYANIDE Ethylenediamine 1-Methyl-2-pyrrolidinone 5-Bromoindole Sodium cyanide Lithium aluminium hydride
Preparation Products
C-(1H-INDOL-5-YL)-METHYLAMINE Suppliers      Global( 27)Suppliers     
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J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
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