|
|
| CAS番号. | 67-68-5 |
| 化学名: | ジメチルスルホキシド |
| 别名: | ジメチルスルホキシド;ジメチルスルホキシド [流動パラフィン試験用];ジメチルスルホキシド [吸光分析用];ヒアズール;デマソルブ;メチルスルホキシド;ドリクール;デメソー;スルフィニルビスメタン;デルタン;ドモソー;ドロミソール;ジメチルスルホキシド(脱水) |
| 英語化学名: | Dimethyl sulfoxide |
| 英語别名: | m176;DMSO;Decap;M 176;Deltan;a10846;Demeso;DMS 70;DMS 90;dms-70 |
| CBNumber: | CB7854105 |
| 分子式: | C2H6OS |
| 分子量: | 78.13 |
| MOL File: | 67-68-5.mol |
|
|
|
|
| ジメチルスルホキシド 物理性質 |
|
|
|
|
| 比重(密度) : |
1.100 g/mL at 20 °C
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 外見 : |
liquid (temperature dependent)
|
|
|
|
|
|
|
|
|
|
|
|
| 安定性：: |
Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic. |
|
|
|
|
|
|
|
|
ジメチルスルホキシド 化学特性,用途語,生産方法 |
|
|
使用
DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). |
|
使用
Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers |
|
使用
Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR. |
|
使用
A polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. |
|
使用
Suitable for HPLC, spectrophotometry, environmental testing |
|
一般的な説明
A clear liquid, essentially odorless. Closed cup flash point 192°F. Vapors are heavier than air. Contact with the skin may cause stinging and burning and lead to an odor of garlic on the breath. An excellent solvent that can transport toxic solutes through the skin. High vapor concentrations may cause headache, dizziness, and sedation. |
|
空気と水の反応
Denser than water and miscible in water. |
|
反応プロフィール
Dimethyl sulfoxide decomposes violently on contact with many acyl halides, aryl halides and related compounds such as phenyl and tolyl chloride, acetyl chloride, benzenesulfonyl chloride, benzoyl chloride, cyanuric chloride, phosphorus chloride, phosphorus oxychloride, and thionyl chloride [Chem. Eng. News 35(9):87 (1957)]. Reacts, possibly violently, with iodine pentafluoride [Chem. Eng. News 47(12):, 109(1969)]. Vacuum distillation from anhydrous magnesium perchlorate led to an explosion [MCA Case History 1187(1966)]. Violently reactive with fluorinating agents such as silver fluoride [Chem. Eng. News 44(24):7(1956)]. Can explode with sodium hydride [Chem. Eng. News 44(24):7(1966)]. Mixture with methyl bromide resulted in an explosion that shattered the apparatus [NFPA 491M, 1991]. Forms salts with perchloric acid that are explosive when dry [Chem. Abst. 44:p3935d (1950)]. Decomposes when heated above normal boiling point. |
|
健康ハザード
Slight eye irritation. |
|
火災危険
Special Hazards of Combustion Products: Sulfur dioxide, formaldehyde, and methyl mercaptan can form |
|
生物活性
Solvent with wide ranging applications in biological research. |
|
|
| ジメチルスルホキシド 生産企業 Global( 322)Suppliers |
|
|
|
|
|