| Company Name: | NCE Biomedical Co.,Ltd. Gold |
| Tel: | 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988 |
| Email: | sales@ncebiomed.com |
| Products Intro: |
Product Name:Ponatinib hybrochloride; AP24534 hybrochloride;Ponatinib;3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
CAS:943319-70-8
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0010 |
| Company Name: | ShangHai Biochempartner Co.,Ltd Gold |
| Tel: | +86 13818785766，400-021-9906 |
| Email: | gaoqing@biochempartner.com |
| Products Intro: |
Product Name:AP24534(Ponatinib)
CAS:943319-70-8
Purity:>98% .NMR+LCMS Package:50Mg/100Mg/500Mg/1g/5g/10g/ |
| Company Name: | Jinan Trio PharmaTech Co., Ltd. Gold |
| Tel: | +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083; |
| Email: | sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) |
| Products Intro: |
Product Name:PONATINIB
CAS:943319-70-8
Purity:99% HPLC Package:1G;10G;100G;500G;1KG |
| Company Name: | Wuhan Biocar Bio-Pharm Co., Ltd. Gold |
| Tel: | 15377519203 |
| Email: | newbio@biocar.cn |
| Products Intro: |
Product Name:Ponatinib
CAS:943319-70-8
Purity:99% Package:>=1g 1200/g |
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| | AP24534(Ponatinib) Basic information |
| | AP24534(Ponatinib) Chemical Properties |
| | AP24534(Ponatinib) Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Usage | AP24534 is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, 2, 1.5, 2.2, 1.1, 1and 0.24 nM for native pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosphorylation and LYN. | | Usage | Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors. | | Usage | Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively |
| | AP24534(Ponatinib) Preparation Products And Raw materials |
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