公司名称: |
百灵威科技有限公司 |
联系电话: |
400-666-7788 +86-10-82848833 |
产品介绍: |
英文名称:HyMenialdisine Analogue #1 CAS:693222-51-4 包装信息:10Mg,1Mg 备注:化学试剂、精细化学品、医药中间体、材料中间体 |
公司名称: |
凯试(上海)科技有限公司 |
联系电话: |
021-50135380 |
产品介绍: |
英文名称:HyMenialdisine Analogue #1 CAS:693222-51-4 纯度:98% 备注:2300元/1mg; 14000元/10mg |
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中文名称: | | 中文同义词: | | 英文名称: | HYMENIALDISINE ANALOGUE #1 | 英文同义词: | HYMENIALDISINE ANALOGUE #1;5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one;5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-β]indol-1-one | CAS号: | 693222-51-4 | 分子式: | C15H12N5O2 | 分子量: | 294.28808 | EINECS号: | | 相关类别: | Protein Kinase Inhibitors and Activators;Tyrosine Kinase Inhibitors |
| HYMENIALDISINE ANALOGUE #1 性质 |
用途 | The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3螔, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar con
centrations. This compound exhibits very potent inhibition of Chk2 activity in the low nanomolar range (IC50=8nM). Exhibits an increased selectivity for the checkpoint kinases over natural Hymeniald
isine. |
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