Product Identification | Back to Contents | 【Product Name】
Temozolomide | 【Synonyms】
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo M & B 39831 MB-39831 Methazolastone | 【CAS】
85622-93-1 | 【Formula】
C6H6N6O2 | 【Molecular Weight】
194.15 | 【RTECS】
NJ5927050 | 【Merck】
12,9289 | 【Beilstein/Gmelin】
5547136 |
Physical and Chemical Properties | Back to Contents | 【Solubility in water】
Slightly soluble | 【Vapor Pressure】
3.5E-11 (25 C) | 【Density】
1.97 g/cm3 (20 C) | 【pKa/pKb】
15.29 (pKa) | 【Partition Coefficient】
-1.15 | 【Usage】
Used for the treatment of refractory anaplastic astrocytoma -- a type of cancerous brain tumor. |
Hazards Identification | Back to Contents | 【Inhalation】
Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. | 【Skin】
Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention. | 【Eyes】
Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice. | 【Ingestion】
If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice. |
Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes. |
Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete. |
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