| Product Identification | Back to Contents | 【Product Name】
Doxycycline | 【Synonyms】
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
6-Deoxy-5-hydroxytetracycline
6-Deoxytetracycline
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
Doxycyclin hyclate | 【CAS】
564-25-0 | 【Formula】
C22H24N2O8 | 【Molecular Weight】
444.44 | 【EINECS】
209-271-1 | 【RTECS】
QI8650000 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,3496 | 【Beilstein/Gmelin】
2230419 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Yellow, crystalline powder with slight ethanolic odor. | 【Solubility in water】
Slightly soluble | 【Vapor Pressure】
2E-24 (25 C) | 【pKa/pKb】
4.50 (pKa) | 【Partition Coefficient】
-.26 | 【Usage】
Medication. |
| First Aid Measures | Back to Contents | 【Ingestion】
Flush mouth out with water. Seek medical attention. | 【Inhalation】
Remove to fresh air. | 【Skin】
Flush with copious amounts of water for at least 15 minutes. | 【Eyes】
Flush with copious amounts of water for at least 15 minutes. |
| Handling and Storage | Back to Contents | 【Storage】
store in a tightly closed container. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Allergic reaction. Irritation. | 【Skin】
Skin hyperpigmentation has been reported. | 【Eyes】
Irritation. | 【Ingestion】
Nausea, vomiting, epigastric burning, and abdominal discomfort have been noted. Tetracycline and doxycycline have been implicated in causing esophageal ulceration, but this is thought to be uncommon. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Rubber or vinyl gloves, safety goggles and appropriate laboratory clothings. | 【Respirators】
NIOSH approved respirator. | 【Exposure Effects】
Headache, papilledema and benign intracranial hypertension have been reported. Maternal ingestion of tetracyclines during pregnancy may cause tooth discoloration, enamel defects, and other congenital anomalies. <br>Hepatotoxicity, pancreatitis, and renal failure may occur in pregnant women following ingestion of tetracyclines during pregnancy. |
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| Company Name: | China Langchem Inc. |
| Tel: | 0086-21-58956006,021-58950017;021-38701807 |
| Fax: | 0086-21-58956100 |
| WebSite: | www.langchem.com |
| Company Name: | Richest Group Limited |
| Tel: | +86 21 5017 5386/3175 7285/86/87/88/89 |
| Fax: | +86 21 6085 3086 |
| WebSite: | www.richest-group.com |
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