Amlodipine besilate

CAS No.	111470-99-6
Chemical Name:	Amlodipine besilate
Synonyms:	Amlor;Amcard;Lowrac;Norvas;Vazkor;NORVASC;Amdepin;Amdipin;Amlodin;Amlopin
CBNumber:	CB4127875
Molecular Formula:	C26H31ClN2O8S
Formula Weight:	567.05
MOL File:	111470-99-6.mol

Amlodipine besilate Property

mp :

199-201°C

storage temp. :

Store at RT

solubility :

DMSO: 20 mg/mL

form :

solid

color :

white

CAS DataBase Reference:

111470-99-6(CAS DataBase Reference)

Safety

Hazard Codes :

Risk Statements :

22-36/37/38-20/21/22

Safety Statements :

26-36

WGK Germany :

RTECS :

US7967700

Hazardous Substances Data:

111470-99-6(Hazardous Substances Data)

Amlodipine besilate Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid

Usage
A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive

Usage
Angiotensin II inhibitor prodrug, antihypertensive

Usage
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.

Biological Activity
L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).

Amlodipine besilate Preparation Products And Raw materials

Raw materials

Preparation Products

Amlodipine besilate Suppliers Global( 214)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Boen pharm	86 512-62572107 62962707	86 512-62922078	sales@boenpharm.com	CHINA	803	58
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)	+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)	sh@meryer.com	CHINA	40407	62
INTATRADE GmbH	+49 3493/605464	+49 3493/605470	sales@intatrade.de	GERMANY	3590	66
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
TCI (Shanghai) Development Co., Ltd.	--	--	info@chemicalbook.com	CHINA	22159	81
BeiJing Hwrk Chemicals Limted	4006990298 010-57411839 020-31335234 021-51691807	010-87653215 0757-86311057 021-55236763	sales@hwrkchemical.com	CHINA	12649	55
Energy Chemical	021-58432009 / 400-005-6266	021-58436166-800	info@energy-chemical.com	CHINA	44198	61
Secco work (Beijing) chemical technology co., LTD	010-69755668; 62507480	010-69755668	1139670422@qq.com	CHINA	3551	54

111470-99-6(Amlodipine besilate)Related Search:

1-PIPERIDINEPROPANENITRILE, 4-METHYL-3-(METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINO)-BETA-OXO-, (3R,4R)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1) ABT-199 Felodipine Fingolimod hydrochloride BIRB 796 (Doramapimod) Z-VAD-FMK 3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid TELMISARTAN Enalapril Amlodipine (S)-Amlodipine Amlodipine mesylate Amlodipine besilate Azabenzene Benzenesulfonic acid AMLODIPINE BESILATE IMP.D (EP): 3-ETHYL-5-METHYL 2-[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYLPYRIDINE-3,5-DICARBOXYLATE

2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate 111470-99-6 Cell Signaling and Neuroscience Calcium Channel Modulators Cell Biology BioChemical AMLODIPINE BENZENESULFONATE AMLODIPINE BESILATE AMLODIPINE BESYLATE NORVASC Ion Channels Inhibitors and Activators Voltage-gated Ion Channels 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1, 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate AMLODIPINE BESILATE MM(CRM STANDARD) AMLODIPINE BESYLATE EPY(CRM STANDARD) C20H25ClN2O5C6H6O3S 11470-99-6 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE) (+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate Amcard Amdepin Amdipin Amlodin Amlopin Amlor Amlosyn Antacal Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1) Calchek Lowrac Monopina Norvas Norvask Tensivask UK 48340-26 C26H31ClN2O8S Active Pharmaceutical Ingredients 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate Ethyl 2-[(2-aminoethoxy)methyl]-4-(2-chloropohenyl)-1,4-dihydro-5-(methoxycarbonyl)-6-methylpyridine-3-carboxylate benzenesulphonate Dihydropyridine Class Chemicals Intermediates & Fine Chemicals Pharmaceuticals Amlodipine 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl·benzenesulfonic acid C20H25ClN2O5C6H5SO3H Aromatics Dihydropyridine Heterocycles 111470-99-6 Amlodipine Besylate (350 mg) Vazkor 3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona 3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate