PHYSOSTIGMINE

CAS No.	57-47-6
Chemical Name:	PHYSOSTIGMINE
Synonyms:	Ezerin;cs58525;mcv4484;ESERINE;Cogmine;CS 58525;Erserine;nih10421;Synapton;Physostol
CBNumber:	CB8770121
Molecular Formula:	C15H21N3O2
Formula Weight:	275.35
MOL File:	57-47-6.mol

PHYSOSTIGMINE Property

mp :	102-104 °C(lit.)

density :

1.166±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. :

2-8°C

Merck :

7384

CAS DataBase Reference:

57-47-6(CAS DataBase Reference)

Safety

Hazard Codes :

T+

Risk Statements :

26/28

Safety Statements :

23-45-25

RIDADR :

UN 1544 6.1/PG 1

WGK Germany :

RTECS :

TJ2100000

F :

8-10

HazardClass :

6.1(a)

PackingGroup :

PHYSOSTIGMINE Chemical Properties,Usage,Production

Chemical Properties
solid

Usage
Physostigmine base (Eserine-Base) is used as bulk pharmaceuticals (parasympathomimetic, cholinergic, ophthalmic, anti-Alzheimer). Product Data Sheet

Usage
It is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying.

General Description
White, odorless, microcrystalline powder. Used as a cholinergic (anticholinesterase) agent and as a veterinary medication.

Health Hazard
Super toxic. Probable oral lethal dose is less than 5 mg/kg for a 70 kg (150 lb.) person. Material is a cholinesterase inhibitor. Effects of exposure may involve the respiratory, gastrointestinal, cardiovascular and central nervous systems. Death occurs due to respiratory paralysis or impaired cardiac function. Time to death may vary from 5 minutes to 24 hours, in severely poisoned patients, depending on factors such as the dose and route. Persons with asthma and/or persons that require drugs containing choline esters are at risk.

Fire Hazard
PHYSOSTIGMINE is a slight fire hazard. When heated to decomposition PHYSOSTIGMINE emits toxic fumes of nitrogen oxides. Keep from light and heat.

PHYSOSTIGMINE Preparation Products And Raw materials

Raw materials
ZINC Hydrogen peroxide

Preparation Products

PHYSOSTIGMINE Suppliers Global( 60)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
BEST-REAGENT	028-85973071 028-85973075	028-85973075	service@best-reagent.com	CHINA	9961	57
Sinopharm Chemical Reagent Co,Ltd.	86-21-63210123	86-21-63290778 86-21-63218885	sj_scrc@sinopharm.com	CHINA	10006	79
Spectrum Chemical Manufacturing Corp.	021-67601398-808	021-57711696	gduan@spectrumchina.net	CHINA	9357	60
Jinan Haohua Industry Co., Ltd	0531-58773082 ;58773060	0531-58773099	sales@jnhaohua.com	CHINA	5672	58
ShangHai YuanYe Biotechnology Co., Ltd.	021-61312847 qq：2797782341	021-60137357	2797782341@qq.com	CHINA	7597	60
Chengdu Ai Keda Chemical Technology Co., Ltd.	4008-755-333 ; 028-86676798 ; 028-86757656	028-86757656	aikeshiji@163.com	CHINA	9909	55
Beijing HuaMeiHuLiBiological Chemical	010-56205725;010-86181995	010-65763397	waley188@sohu.com	CHINA	12409	58
TCI Japan	03-3668-0489	03-3668-0520	sales@tokyokasei.co.jp	JAPAN	24828	80

57-47-6(PHYSOSTIGMINE)Related Search:

physostigmine methiodide Physostigmine-D3 PHYSOSTIGMINE-D3 (N-METHYL-D3-CARBAMOYL) physostigmine heptyl PHYSOSTIGMINE HEMISULFATE,PHYSOSTIGMINE SULFATE,PHYSOSTIGMINE HEMISULFATE SALT Physostigmine salicylate (Eserine salicylate),physostigmine,[salicylate(1:1) PHYSOSTIGMINE (-)-N-METHYLPHYSOSTIGMINE PHYSOSTIGMINE HYDROCHLORIDE PHENSERINE PHYSOSTIGMINE HYDROBROMIDE

(3as-cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-olmeth (3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-olmethylcarbamate (ester) 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo-[2,3-b]indol-5-yl methylcarbamate 1,2,3,3abeta,8abeta-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]-indol-5-yl methylcarbamate 1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate 3-b)indol-5-ol,1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-pyrrolo(methylcarb Antilirium calabarine Carbamic acid, methyl-, ester with eseroline Cogmine Eserine CS 58525 cs58525 Erserine Eserolein, methylcarbamate Eserolein, methylcarbamate (ester) eserolein,methylcarbamate(ester) Esromiotin Ezerin Fysostigmin mcv4484 methyl-carbamicacid,esterwitheseroline methyl-carbamicaciesterwitheseroline nih10421 Physostol Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)- Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate, (3aS-cis)- ylcarbamate(ester) Indole Alkaloids Alkaloids 57-47-6 ESERINE PHYSOSTIGMINE Physostigminefree base Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly. Physosfigmine ESERINE FREE BASE C15H21N3O2 PHYSOSTIGMINE95%,99% Cogmine NSC 30782 Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS,8aR)- (9CI) Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)- Pyrrolo[2,3-b]indol-5-old,1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-,methylcarbamate(ester),(3aS-cis)- PHSOSTIGMINE AKA ESERINE Alkaloids Biochemistry Indole Alkaloids Physostigmine base (Eserine base) Eserine【alkaloid】 Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester Methylcarbamic acid (3aS)-1,2,3,3aα,8,8aα-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl ester Methylcarbamic acid (3aS)-1,2,3,3aα,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate N-methylcarbamic acid [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] ester ESERINE(RG) Physostigmine ,98% Eserine,Physostigmine Intermediates & Fine Chemicals