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| | Aconitine Basic information |
| Product Name: | Aconitine | | Synonyms: | (1ALPHA,3ALPHA,6ALPHA,14ALPHA,15ALPHA,16BETA)-20-ETHYL-1,6,16-TRIMETHOXY-4-(METHOXYMETHYL)ACONITANE-3,8,13,14,15-PENTOL 8-ACETATE 14-BENZOATE;ACETYLBENZOYLACONINE;ACONITIN;ACONITINE;ACONITANE;ACONITANE-3,8,13,14,15-PENTOL,20-ETHYL-1,6,16-TRIMETHOXY-4-(METHOXYMETHYL)-,8-ACETATE14-BENZOATE,(1ALPHA,3ALPHA,6ALPHA,14ALPHA,15ALPHA,16BETA)-;aconitincristallisat;aconitine(crystalline) | | CAS: | 302-27-2 | | MF: | C34H47NO11 | | MW: | 645.74 | | EINECS: | 206-121-7 | | Product Categories: | Alkaloids;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Amines, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 302-27-2.mol |  |
| | Aconitine Chemical Properties |
| mp | 200-205 °C (dec.)
| | storage temp. | Refrigerator | | Merck | 13,120 | | NIST Chemistry Reference | Aconitine(302-27-2) |
| | Aconitine Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Usage | anesthetic (gastric), antipyretic, and cardiotoxin | | Usage | Neurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and dec
reases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In c
ultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization.
Used in producing heart arrhythmia in experimental anim
als. |
| | Aconitine Preparation Products And Raw materials |
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