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| Products Intro: |
Product Name:Dexamethasone
CAS:50-02-2
Purity:99% Package:1公斤/铝箔袋 |
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| | Dexamethasone Basic information |
| Product Name: | Dexamethasone | | Synonyms: | 16alpha)-;16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet;16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-2,20-dione;16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2;16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione;16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-dien;16alpha-Methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione;16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol | | CAS: | 50-02-2 | | MF: | C22H29FO5 | | MW: | 392.46 | | EINECS: | 200-003-9 | | Product Categories: | Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Steroid and Hormone;Pharmaceutical intermediate;API;MAXIDEX;Hormone Drugs;Mainly used for anti-inflammatory and allergy | | Mol File: | 50-02-2.mol |  |
| | Dexamethasone Chemical Properties |
| mp | 262-264 °C(lit.)
| | alpha | 75 º (c=1, dioxane) | | refractive index | 76 ° (C=1, Dioxane) | | storage temp. | 2-8°C
| | solubility | ethanol: 1 mg/mL
| | form | powder
| | color | off-white
| | Water Solubility | 10 mg/100 mL (25 ºC) | | Merck | 14,2943 | | BRN | 2066651 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. | | CAS DataBase Reference | 50-02-2(CAS DataBase Reference) | | NIST Chemistry Reference | Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) | | EPA Substance Registry System | Pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17,21-trihydroxy- 16-methyl-, (11.beta.,16.alpha.)-(50-02-2) |
| | Dexamethasone Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Usage | A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase | | Usage | Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthas
e. | | General Description | Odorless white to off-white crystalline powder with a slightly bitter taste. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | Dexamethasone may be sensitive to prolonged exposure to light. Dexamethasone is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides. Oxidation may occur with bases. | | Fire Hazard | Flash point data for Dexamethasone are not available; however, Dexamethasone is probably combustible. | | Biological Activity | Glucocorticoid; anti-inflammatory. Reduces levels of activated NF- κ B in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. |
| | Dexamethasone Preparation Products And Raw materials |
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