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Topiramate

Topiramate Suppliers list
Company Name:Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd  Gold
Tel:010-64430626/13801208576
Email:maggie@chinazhongshuo.com
Products Intro: Product Name:Topiramate
CAS:97240-79-4
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:TopiraMate
CAS:97240-79-4
Purity:99% Package:100MG
Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel:+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Email:sh@meryer.com
Products Intro: Product Name:TopiraMate
CAS:97240-79-4
Purity:>98.0%(LC)(T) Package:1g;5g Remarks:T2755
Company Name:INTATRADE GmbH  
Tel:+49 3493/605464
Email:sales@intatrade.de
Products Intro: Product Name:Topiramate Synonyms Topamax; 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
CAS:97240-79-4
Remarks:PS03336
Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:67055399@qq.com
Products Intro: Product Name:TopiraMate;2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fructopyranosesulfaMate
CAS:97240-79-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Topiramate Basic information
Product Name:Topiramate
Synonyms:2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate;MCN 4853;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE;2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE;RWJ 17021;RWJ-17021-000
CAS:97240-79-4
MF:C12H21NO8S
MW:339.36
EINECS:200-659-6
Product Categories:Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Mol File:97240-79-4.mol
Topiramate Structure
Topiramate Chemical Properties
mp 125°C
storage temp. 2-8°C
solubility DMSO: ~44 mg/mL
form solid
color white
Safety Information
Hazard Codes Xi,T,F
Risk Statements 36/37/38-39/23/24/25-23/24/25-11
Safety Statements 26-36-45-36/37-16-7
WGK Germany 3
RTECS LS7083000
Hazardous Substances Data97240-79-4(Hazardous Substances Data)
MSDS Information
ProviderLanguage
RWJ-17021 English
SigmaAldrich English
Topiramate Usage And Synthesis
Chemical PropertiesWhite-to-Off-White Crystalline Powder
Usageanticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor
UsageUsed for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. Qsymia? is indicated for the treat
UsageUsed as an anticonvulsant
Biological ActivityAnticonvulsant. Antagonizes GluR5 kainate receptors (IC 50 = 0.46 μ M), acts as a positive allosteric modulator of GABA A receptor-mediated currents, inhibits Na v channels (IC 50 = 48.9 μ M) and inhibits L-type Ca 2+ channels. Also inhibits carbonic anhydrase (CA) (K i values are 0.1 and 0.2 μ M at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
Topiramate Preparation Products And Raw materials
Tag:Topiramate(97240-79-4) Related Product Information
ACY-1215 (E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE Lomefloxacin hydrochloride Nisoldipine Entinostat Z-VAD-FMK Sulfamic acid beta-D-Fructopyranose Topiramate hydrochloride 4,5-Desisopropylidene Topiramate 2,3-Desisopropylidene Topiramate Topiramate2,3:4,5-Bis-O-(1-MethylEthylidene)-B- Topiramate Related Compound A TOPIRAMATE-D12 Topiramate 2,3:4,5 Bis-O-(1-Methyl ethylidene)-Fructopyranose azido sulphate 10-Hydroxy Topiramate,R-Hydroxy Topiramate 9-Hydroxy Topiramate,S-Hydroxy Topiramate