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Gefitinib

Gefitinib Suppliers list
Company Name:Chengdu Green Young Biomedical Technology Co., Ltd.  Gold
Tel:86+28-85337952 18081025021
Email:greenyoung@glykj.com. Skype:greenyoung777
Products Intro: Product Name:Gefitinib
CAS:184475-35-2
Package:100g 500 g 1kg
Company Name:Nanjing First Pharmaceutical Co., Ltd.  Gold
Tel:+86-25-83172655 /13776562784
Email:sales@njfirstpharm.com
Products Intro: Product Name:Gefitinib
CAS:184475-35-2
Purity:>99% Package:1g;5g;10g;25g;100g;250g;500g;1kg;10kg;25kg;50kg;100kg Remarks:Available in stock
Company Name:Guangzhou Isun Pharmaceutical Co., Ltd  Gold
Tel:020-39119399 18927568969
Email:isunpharm@qq.com, isunpharm@hotmail.com
Products Intro: Product Name:Gefitinib
CAS:184475-35-2
Purity:>98% Package:1g;5g;50g;500g;5kg;25kg
Company Name:Wuhan Hezhong Bio-chemical Manufacture co ltd  Gold
Tel:021-68580270 / 18121115343
Email:foodinfo@yccreate.com
Products Intro: Product Name:Gefitinib
CAS:184475-35-2
Purity:99% HPLC Package:100G;500G;1KG;5KG
Company Name:Jinan XuanHong Pharmaceutical Technology Co.,Ltd  Gold
Tel:0531-88801867/1869,18678775975
Email:sciencechem@163.com
Products Intro: Product Name:Gefitinib
CAS:184475-35-2
Purity:99% Package:5g,10g,50g,100,500g,1kg,5kg
Gefitinib Basic information
Product Name:Gefitinib
Synonyms:IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;Gefitinib(TINIBS)
CAS:184475-35-2
MF:C22H24ClFN4O3
MW:446.9
EINECS:
Product Categories:Active Pharmaceutical Ingredients;Gefitinib;Molecular Targeted Antineoplastic;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;APIs;IRESSA;Anti-cancer&immunity;API
Mol File:184475-35-2.mol
Gefitinib Structure
Gefitinib Chemical Properties
mp 119-1200C
storage temp. Store at RT
CAS DataBase Reference184475-35-2(CAS DataBase Reference)
Safety Information
MSDS Information
Gefitinib Usage And Synthesis
Chemical PropertiesLight-Yellow Crystalline Powder
UsageGefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.
UsageGefitinib is an antineoplastic.
Biological ActivityOrally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts.
Gefitinib Preparation Products And Raw materials
Tag:Gefitinib(184475-35-2) Related Product Information
Diphenyl oxide (Trifluoromethoxy)benzene Guaiacol Anisole Anisic aldehyde PHENYL VALERATE Fluorine 4-Methoxybenzyl cyanide PHENYL RESIN Difluorochloromethane Phenylacetic acid 4-Methoxyphenol Gefitinib O-Methyl-D3 O-Desmorpholinopropyl Gefitinib O-Desmethyl Gefitinib AG 1478 HYDROCHLORIDE Gefitinib p-Anisidine