L-Hydroxyproline

Company Name:	Alfa Aesar Gold
Tel:	400-610-6006; 021-67582000
Email:	saleschina@alfa-asia.com
Products Intro:	Product Name:trans-4-Hydroxy-L-proline, 99+% CAS:51-35-4 Package:10g Remarks:A11851

Company Name:	Wuxi Zhongkun Biochemical Technology Co., Ltd. Gold
Tel:	0510-85629785,0510-66893528,0510-66892159,18051932136
Email:	saleschem@zhk-bio.com
Products Intro:	Product Name:L-Hydroxyproline CAS:51-35-4 Purity:99% HPLC Package:5KG;1KG

Company Name:	Beijing Holiyang Chemical Co. Ltd. Gold
Tel:	010-56108838 56108878
Email:	holiyangchem@163.com
Products Intro:	CAS:51-35-4

Company Name:	J & K SCIENTIFIC LTD.
Tel:	400-666-7788 +86-10-82848833
Email:	jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro:	Product Name:trans-4-Hydroxy-L-proline CAS:51-35-4 Purity:99% Package:100G,25G,500G

Company Name:	Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:	+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Email:	sh@meryer.com
Products Intro:	Product Name:L-Hydroxyproline CAS:51-35-4 Purity:98% Package:25g;100g Remarks:I70027

L-Hydroxyproline Basic information

Product Name:	L-Hydroxyproline
Synonyms:	4-Hydroxyproline;4-L-Hydroxyproline;delta-Hydroxyproline;Hypro;L-Proline, 4-hydroxy-, trans-;L-Proline,4-hydroxy-,trans;Ls-Hydroxyproline;Proline, 4-hydroxy-
CAS:	51-35-4
MF:	C5H9NO3
MW:	131.13
EINECS:	200-091-9
Product Categories:	Nitrogen cyclic compounds;PHARMACEUTICALS;Amino Acids;Pyrrole&Pyrrolidine&Pyrroline;Hydroxyproline [Hyp];Unusual Amino Acids;Biochemistry;Biological-modified Amino Acids;L-Amino Acids;Amino Acids;Amino Acids & Derivatives;Chiral Reagents;Heterocycles
Mol File:	51-35-4.mol

L-Hydroxyproline Chemical Properties

mp	273 °C (dec.)(lit.)
alpha	-75.5 º (c=5, H2O)
refractive index	-75.5 ° (C=4, H2O)
storage temp.	Store at RT.
solubility	H₂O: 50 mg/mL
Water Solubility	357.8 g/L (20 º C)
Merck	14,4840
BRN	471933
CAS DataBase Reference	51-35-4(CAS DataBase Reference)
NIST Chemistry Reference	Hydroxyproline(51-35-4)
EPA Substance Registry System	L-Proline, 4-hydroxy-, (4R)-(51-35-4)

Safety Information

MSDS Information

Provider	Language
(2S,4R)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

L-Hydroxyproline Usage And Synthesis

Chemical Properties	White crystalline powder
Usage	A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.

L-Hydroxyproline Preparation Products And Raw materials

Preparation Products	(R)-(-)-3-Pyrrolidinol hydrochloride-->N-Boc-cis-4-Hydroxy-L-proline methyl ester-->(2S,4S)-(-)-N-BOC-4-Diphenylphosphino-2-diphenylphosphinomethyl-pyrrolidine
Raw materials	Α-PROTEIN-->Casein-->Gelatin-->Soy bean Isoflavone Isoflavone 10-40%-->Bone glue

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