| Company Name: | Dalian Meilun Biotech Co., Ltd. Gold |
| Tel: | 0411-66771943；0411-66771942 |
| Email: | sales@meilune.com |
| Products Intro: |
Product Name:ActinoMycin D
CAS:50-76-0
Purity:98% Package:5MG 380, 25MG 980 |
| Company Name: | Hangzhou J&H Chemical Co., Ltd. Gold |
| Tel: | +86-0571-87396432 87396430 sales@jhechem.com; |
| Email: | sales@jhechem.com; |
| Products Intro: |
Product Name:ACTINOMYCIN D
CAS:50-76-0
Purity:97%min Package:1g 5g 10g 50g 100g Remarks:Appearence:a bright red crystalline powder;Total impurity:5%max;Specific rotation:-292deg to -317deg;Loss on drying:5%max |
| Company Name: | Shanghai Boyle Chemical Co., Ltd. Gold |
| Tel: | Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market) |
| Email: | sales@boylechem.com |
| Products Intro: |
Product Name:Actinomycin D
CAS:50-76-0
Purity:95%min Package:100G,1KG.5KG |
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| | Actinomycin D Basic information |
| | Actinomycin D Chemical Properties |
| mp | 251-253 °C
| | storage temp. | 2-8°C
| | solubility | ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
| | form | powder
| | color | red, powder
| | Water Solubility | SOLUBLE | | Merck | 13,2828 | | Stability: | Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible. | | CAS DataBase Reference | 50-76-0(CAS DataBase Reference) | | EPA Substance Registry System | Actinomycin D(50-76-0) |
| | Actinomycin D Usage And Synthesis |
| Chemical Properties | red crystalline powder | | Usage | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. | | Usage | antineoplastic, intercalating agent | | Usage | Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumour activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumour cell death has been demonstrated to occur by apoptosis. | | Usage | Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumor activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumor cell death has been demonstrated to occur by apoptosis. | | Usage | Antibiotic substance belonging to the actinomycin complex, produced by several Streptomyces spp. Antineoplastic | | General Description | Bright red rhomboid prisms or red powder. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | Actinomycin D can react with strong oxidizing agents, strong acids and strong bases. | | Fire Hazard | Flash point data for Actinomycin D are not available. Actinomycin D is probably combustible. | | Biological Activity | Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis. |
| | Actinomycin D Preparation Products And Raw materials |
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