Ethyl cyanoacetate

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Company Name:Shanghai Yolne Chemical Co., Ltd.  Gold
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Products Intro: CAS:105-56-6
Purity:98% Package:100g;500g;1Kg
Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD  Gold
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Products Intro: Product Name:Ethyl cyanoacetate
CAS:105-56-6
Purity:99% Package:500ML,100ML,2.5L
Company Name:Shanghai Kaisai Chemical Co., Ltd  Gold
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Products Intro: CAS:105-56-6
Company Name:Weifang QianJin Fine Chemical Co., Ltd.  Gold
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Products Intro: Product Name:Cyanoacetic acid ethyl ester
CAS:105-56-6
Purity:99.9% GC Package:1kg 5kg10kg 25kg
Company Name:Chengdu DingDang Pharmaceutical Co., Ltd.  Gold
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Products Intro: Product Name:Ethyl cyanoacetate
CAS:105-56-6
Purity:98% Package:50g,1000g,5kg
Ethyl cyanoacetate Basic information
Product Name:Ethyl cyanoacetate
Synonyms:2-cyano-aceticacidethylester;Acetic acid,2-cyano-, ethyl ester;Aceticacid,cyano-,ethylester;Cyanacetate ethyle;cyanacetateethyle;Cyanessigester;cyanoacetated’ethyle;Cyanoacetic ester
CAS:105-56-6
MF:C5H7NO2
MW:113.11
EINECS:203-309-0
Product Categories:Pharmaceutical Intermediates;C2 to C5;Carbonyl Compounds;Esters;Alpha Sort;Chemical Class;E;E-LAlphabetic;EQ - EZAnalytical Standards;EstersAnalytical Standards;Nitriles;Volatiles/ Semivolatiles;organic chemical
Mol File:105-56-6.mol
Ethyl cyanoacetate Structure
Ethyl cyanoacetate Chemical Properties
mp -22 °C
bp 208-210 °C(lit.)
density 1.063 g/mL at 25 °C(lit.)
vapor density 3.9 (vs air)
vapor pressure 1 mm Hg ( 67.8 °C)
refractive index n20/D 1.418(lit.)
Fp >230 °F
Water Solubility 20 g/L (20 ºC)
Merck 14,3786
BRN 605871
CAS DataBase Reference105-56-6(CAS DataBase Reference)
NIST Chemistry ReferenceAcetic acid, cyano-, ethyl ester(105-56-6)
EPA Substance Registry SystemAcetic acid, cyano-, ethyl ester(105-56-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/38
Safety Statements 36/37-37/39-26
RIDADR 3276
WGK Germany 1
RTECS AG4110000
10
Hazardous Substances Data105-56-6(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Ethyl 2-cyanoacetate English
SigmaAldrich English
ACROS English
ALFA English
Ethyl cyanoacetate Usage And Synthesis
Chemical Propertiesclear liquid
UsageReagent used in labelled pyrimidine and purine synthesis.
General DescriptionA colorless liquid. Denser than water. Contact may irritate skin, eyes and mucous membranes. Flash point 210°F. May be toxic by ingestion. Used to make other chemicals.
Air & Water ReactionsSlightly soluble in water.
Reactivity ProfileEthyl cyanoacetate is both a nitrile and an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.
Health HazardTOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardCombustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Ethyl cyanoacetate Preparation Products And Raw materials
Raw materialsEtanol-->Hydrochloric acid-->Sulfuric acid -->Sodium cyanide-->Chloroacetic acid-->Ethyl chloroacetate-->Chloroacetic acid sodium salt-->Cyanoacetic acid
Preparation ProductsEthyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate-->2-AMINO-5-ISOPROPYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->2-AMINO-4-ETHYL-5-METHYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->Dacarbazine-->2,4,7-Triamino-6-phenylpteridine-->2-AMINO-4,6-DIMETHYL-3-PYRIDINECARBOXAMIDE-->Allopurinol-->5-AMINO-4-CYANO-3-METHYL-THIOPHENE-2-CARBOXYLIC ACID ETHYL ESTER-->6-AMINO-2-MERCAPTO-PYRIMIDIN-4-OL-->3-AMINO-2,2-DIMETHYL-1-PROPANOL-->ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE-->1-Cyclohexyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carbonitrile ,97%-->6-AMINO-3-METHYLURACIL-->2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->1,2,3,5-TETRAHYDRO-8-THIA-5,7-DIAZA-CYCLOPENTA[A]INDENE-4-ONE-->5,6-Diamino-1-methyluracil-->6-AMINO-2-METHYLTHIO-3-METHYLURACIL-->5-CYANO-6-HYDROXY-4-METHOXYMETHYL-2-METHYLPYRIDINE-->GUANINE SULFATE-->6-AMINO-1-METHYL-5-NITROSOURACIL-->6-CHLORO-5-CYANO-4-METHOXYMETHYL-3-NITRO-2-PICOLINE-->Ethyl α-cyanoacrylate instantaneous adhesive-->2-CHLORO-4-METHYLQUINOLINE-3-CARBONITRILE-->ETHYL 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE-->6-Amino-1-methyluracil-->2-Amino-4-trifluoromethylbenzonitrile-->ETHYL 5-AMINO-1-PYRIDIN-2-YL-1H-PYRAZOLE-4-CARBOXYLATE-->2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->2-(4,6-diamino-1,3,5-triazin-2-yl)acetic acid-->5-AMINO-3-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER-->1-ETHYL-1-METHYLSUCCINIC ACID-->6-Aminouracil -->Disperse Yellow S-3GL-->Amiloride hydrochloride-->ETHYL 2-CYANO-3-METHYL-2-PENTENOATE-->ETHYL(Z)-2-CYANO-3-ETHOXY-2-PROPENOATE-->4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate-->2-FORMAMIDINO-2-PHENYLDIAZOACETAMIDE HYDROCHLORIDE
Tag:Ethyl cyanoacetate(105-56-6) Related Product Information
CYCLOHEXYL CYANOACETATE Ethylparaben METHOXY ETHYL CYANOACETATE Ethyl isocyanoacetate Ethyl (ethoxymethylene)cyanoacetate Ethyl cyanoglyoxylate-2-oxime Tetraethyl orthosilicate Cyanoacetic acid Ethyl acetate Ethyl acrylate Ethyl formate Ethyl propionate Etanol Trinexapac-ethyl ISOXADIFEN-ETHYL Ethyl cyanoacetate Diethyl ether 2-Ethoxyethanol