(+)-Griseofulvin

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Products Intro: Product Name:(+)-Griseofulvin
CAS:126-07-8
Purity:99.6% Package:25G,5G
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Products Intro: Product Name:Griseofulvin
CAS:126-07-8
Purity:98% HPLC Package:1g;5g;25g;100g
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Products Intro: Product Name:(+)-Griseofulvin, 97%
CAS:126-07-8
Package:5g Remarks:B23521
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Products Intro: Product Name:Griseofulvin
CAS:126-07-8
Purity:98%;99% Package:1g;5g;25g;100g;250g;500g;1kg
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Products Intro: Product Name:(+)-Griseofulvin
CAS:126-07-8
Purity:97.0%(LC) Package:5G;25G
(+)-Griseofulvin Basic information
Product Name:(+)-Griseofulvin
Synonyms:(+)-GRISEOFULVIN;GRISEOFULVIN;[2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE;(2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE;7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE;(+)-griseofulvi;(2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy;(2s-trans)-xy-6’-methyl
CAS:126-07-8
MF:C17H17ClO6
MW:352.77
EINECS:204-767-4
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Antifungal;Aromatics;Chiral Reagents;VERELAN
Mol File:126-07-8.mol
(+)-Griseofulvin Structure
(+)-Griseofulvin Chemical Properties
mp 218-220 °C(lit.)
alpha 354 º (c=1, dimethylform)
storage temp. −20°C
Water Solubility practically insoluble
Merck 14,4549
BRN 95226
CAS DataBase Reference126-07-8(CAS DataBase Reference)
NIST Chemistry ReferenceGriseofulvin(126-07-8)
EPA Substance Registry SystemSpiro[benzofuran- 2(3H),1'-[2]cyclohexene]- 3,4'-dione, 7-chloro-2',4,6-trimethoxy- 6'-methyl-, (1'S,6'R)-(126-07-8)
Safety Information
Hazard Codes T,Xn
Risk Statements 60-61-40-43-45
Safety Statements 53-22-36/37/39-45
WGK Germany 3
RTECS WG9800000
Hazardous Substances Data126-07-8(Hazardous Substances Data)
MSDS Information
ProviderLanguage
(+)-Griseofulvin English
SigmaAldrich English
ACROS English
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(+)-Griseofulvin Usage And Synthesis
Chemical PropertiesCrystalline Solid
Usageadrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic
Usageantifungal, inhibits mitosis in metaphase
UsageGriseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.
UsageIt is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum
General DescriptionWhite to pale cream-colored crystalline powder. Odorless or almost odorless. Tasteless. Sublimes without decomposition at 410°F.
Air & Water ReactionsInsoluble in water.
Reactivity Profile(+)-Griseofulvin is incompatible with strong oxidizing agents. .
Fire HazardFlash point data for (+)-Griseofulvin are not available. (+)-Griseofulvin is probably combustible.
(+)-Griseofulvin Preparation Products And Raw materials
Raw materialsStarch-->Oxalic acid
Tag:(+)-Griseofulvin(126-07-8) Related Product Information
5-CHLORO-2-METHOXYBENZALDEHYDE 1-(3-CHLORO-4-HYDROXYPHENYL)-1-ETHANONE 4'-hydroxy-2-methylpropiophenone 1-(5-CHLORO-2,4-DIMETHOXY-PHENYL)-ETHANONE 4-HYDROXY-2,2-DIMETHYL-BENZOFURAN-3-ONE 3-(3-CHLORO-PHENYL)-PROPAN-1-OL 3'-Chloropropiophenone 3-CHLOROPHENETHYLALCOHOL 1-METHOXYCYCLOHEXENE 2-CHLORO-3-METHOXYPHENOL 1-(4-METHOXYPHENYL)-3-METHYLBUTAN-1-ONE 5-CHLORO-2-METHOXYACETOPHENONE ALLYL 2-CHLOROPHENYL ETHER (+)-Griseofulvin TRANSFAT Difluorochloromethane trans,trans-2,4-Undecadienal Cyclohexene